Atherosclerosis remains one of the greatest silent killers of the modern world. Long before a patient develops chest pain, stroke, heart failure, peripheral arterial disease, or sudden cardiac death, the disease may already be progressing inside the arterial wall. Lipids, inflammation, endothelial dysfunction, thrombosis, genetics, diabetes, hypertension, obesity, renal disease, smoking, and lifestyle factors combine over years to create the dangerous vascular terrain that leads to cardiovascular events.

Modern Lipidology: Advanced Management of Atherosclerosis is written as a practical, advanced, and clinically powerful guide for cardiologists, physicians, diabetologists, lipid specialists, endocrinologists, internists, postgraduate trainees, medical students, and all healthcare professionals involved in cardiovascular prevention and vascular risk management.

This book moves beyond the traditional concept of “cholesterol treatment.” Modern lipidology is no longer limited to prescribing a statin and checking LDL levels. It now includes advanced risk stratification, lifetime cardiovascular risk assessment, plaque biology, apolipoprotein B, lipoprotein(a), triglyceride-rich lipoproteins, non-HDL cholesterol, residual inflammatory risk, genetic dyslipidemias, diabetes-related dyslipidemia, metabolic syndrome, chronic kidney disease, and recurrent atherosclerotic cardiovascular disease despite standard therapy.

The central message of this book is clear: atherosclerosis must be prevented early, detected intelligently, treated aggressively, and followed lifelong. Every patient is different. Some develop severe coronary artery disease with only moderate lipid elevation. Some have strong family history and hidden genetic risk. Some experience recurrent events despite “controlled” LDL cholesterol. Some require combination therapy, injectable agents, lifestyle transformation, and closer surveillance. This book helps clinicians understand these difficult scenarios with clarity and confidence.

Inside this Kindle edition, readers will explore the science and clinical application of lipid management, including LDL cholesterol reduction, high-intensity statin therapy, ezetimibe, PCSK9 inhibitors, inclisiran, bempedoic acid, fibrates, omega-3 fatty acids, lipoprotein(a)-targeted therapies, triglyceride management, familial hypercholesterolemia, secondary prevention after myocardial infarction, post-angioplasty lipid control, post-CABG vascular protection, and lipid care in diabetes, hypertension, obesity, renal disease, and elderly patients.

Special emphasis is placed on practical decision-making. When is LDL “low enough”? When should combination therapy be started? How should statin intolerance be handled? Which patients need apolipoprotein B or lipoprotein(a) testing? How should residual risk be treated after angioplasty? What should be done when a patient has recurrent plaque progression despite good reports? How can lipid therapy be personalized for high-risk and very-high-risk patients?

This book also highlights the modern role of imaging and risk assessment. Coronary calcium scoring, CT coronary angiography, carotid plaque assessment, intravascular imaging, and clinical risk calculators can help identify patients who need more intensive prevention. The goal is not only to treat numbers, but to protect arteries, prevent events, and improve long-term survival.

Written by Dr A M Thirugnanam, Senior Interventional Cardiologist, this book reflects a forward-looking cardiovascular prevention strategy built from real-world clinical practice. It connects lipid science with interventional cardiology, preventive cardiology, metabolic medicine, and patient-centered care.

Modern Lipidology is not just a reference book—it is a clinical roadmap for the future of cardiovascular prevention. For every doctor who wants to reduce heart attacks, prevent strokes, protect stents, slow plaque progression, and manage atherosclerosis with modern precision, this book offers a high-value, practical, and advanced guide.

In the modern era, the best cardiology begins before the blockage, before the infarction, before the emergency. It begins with understanding lipids, inflammation, plaque, and risk—and acting early enough to change the patient’s future.